alpelisib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View alpelisib's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.0038829362
alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	-0.0052492265
alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.012296816
alpelisib Compound (Entity type)	Indication Knowledge Graph Relation (Entity type)	Germline BRCA-mutated, HER2-negative metastatic breast cancer Disease or Phenotype (Entity type)
alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.0058592036
alpelisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	0.5084252953529358
alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.007039212
alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.004672442
alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0046027526
alpelisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	taselisib Compound (Entity type)	0.4958942532539367

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.0038829362

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
-0.0052492265

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.012296816

alpelisib
Compound (Entity type)
Indication
Knowledge Graph Relation (Entity type)
Germline BRCA-mutated, HER2-negative metastatic breast cancer
Disease or Phenotype (Entity type)

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.0058592036

alpelisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
0.5084252953529358

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.007039212

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.004672442

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0046027526

alpelisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
taselisib
Compound (Entity type)
0.4958942532539367

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Knowledge Graph Assertions

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