Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

SLC35E2B (Gene)

Ensembl Gene ID: ENSG00000189339

Entrez Gene ID: 728661

Description: solute carrier family 35 member E2B

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SLC35E2B's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SLC35E2B.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SLC35E2B.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SLC35E2B.

Gene Sets (1281)

LINCS L1000 Chem Pert Consensus Sigs (303)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (8)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (277)

A gene set library provided by LINCS

rummageo gene perturbations (219)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (186)

A gene set library provided by LINCS

rummageo chemical perturbations (288)

A gene set library provided by LINCS

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	CPI-1189 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	-0.00364627
	Duvelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.008442052
	2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0053100036
	raltitrexed Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	-0.008235639
	alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0046027526
	2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0035779346
	KFGENEBIN:SLC35E2B-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)
	apitolisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.009595387
	PIK-90 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.009447755
	4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0072608935

CPI-1189
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
-0.00364627

Duvelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.008442052

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0053100036

raltitrexed
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
-0.008235639

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0046027526

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0035779346

KFGENEBIN:SLC35E2B-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)

apitolisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.009595387

PIK-90
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.009447755

4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0072608935

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.