FEATURED
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
FEATURED
CFDE GMT Crossing: GTEx Aging Signatures vs MoTrPAC Exercise Gene Sets
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity [1]. To investigate the common biological underpinnings of aging and exercise and discover genes that are induced and repressed due to exercise and also change in levels due to aging, we crossed the aging signatures created from GTEx [2] with the MoTrPAC rat endurance training [3] gene sets.
FEATURED
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
FEATURED
CFDE GMT Crossing: GTEx Aging Signatures vs MoTrPAC Exercise Gene Sets
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity [1]. To investigate the common biological underpinnings of aging and exercise and discover genes that are induced and repressed due to exercise and also change in levels due to aging, we crossed the aging signatures created from GTEx [2] with the MoTrPAC rat endurance training [3] gene sets.
FEATURED
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the selected target are queried from several DCCs.
FEATURED
CFDE GMT Crossing: GTEx Aging Signatures vs MoTrPAC Exercise Gene Sets
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity [1]. To investigate the common biological underpinnings of aging and exercise and discover genes that are induced and repressed due to exercise and also change in levels due to aging, we crossed the aging signatures created from GTEx [2] with the MoTrPAC rat endurance training [3] gene sets.
ALL USE CASES
Explore different use cases that utilizes data from different CFDE participating programs
GeneSetCart
Analysis of Alexander Disease Gene Sets
Alexander disease (AxD) is caused by a GFAP gene mutation, leading to an accumulation of GFAP protein. This excess GFAP leads to Rosenthal fibers (RFs) in astrocytes. We use the G2SG pipeline to analyze gene sets created by comparing gene expression samples obtained from GEO of wild type (WT) or controls to Alexander disease samples.
Playbook Workflow Builder
Cell Surface Targets for Individual Cancer Patients Analyzed with Common Fund Datasets
Given RNA-seq samples from a patient tumor, we screen for targets which are highly expressed in the tumor but lowly expressed across all healthy human tissues in GTEx. Detailed information about the the selected target are queried from several DCCs.
@CFDE Workbench 2024
The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
@CFDE Workbench 2024