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alpelisib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View alpelisib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.0038829362
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ATF3 Gene (Entity type)	-0.0052492265
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPP1 Gene (Entity type)	-0.012296816
	alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.0058592036
	alpelisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	0.5084252953529358
	alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS4Y1 Gene (Entity type)	0.007039212
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.004672442
	alpelisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0046027526
	alpelisib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	taselisib Compound (Entity type)	0.4958942532539367
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UCHL1 Gene (Entity type)	-0.0045863576

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.0038829362

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ATF3
Gene (Entity type)
-0.0052492265

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPP1
Gene (Entity type)
-0.012296816

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.0058592036

alpelisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
0.5084252953529358

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS4Y1
Gene (Entity type)
0.007039212

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.004672442

alpelisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0046027526

alpelisib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
taselisib
Compound (Entity type)
0.4958942532539367

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UCHL1
Gene (Entity type)
-0.0045863576

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