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TRIB3 (Gene)

Ensembl Gene ID: ENSG00000101255

Entrez Gene ID: 57761

Description: tribbles pseudokinase 3

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TRIB3's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TRIB3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TRIB3.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TRIB3.

Gene Sets (3861)

LINCS L1000 Chem Pert Consensus Sigs (1248)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (840)

A gene set library provided by LINCS

rummageo gene perturbations (322)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (4)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (1041)

A gene set library provided by LINCS

rummageo chemical perturbations (401)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (3)

A gene set library provided by MoTrPAC

Genotype Tissue Expression

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Tioguanine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.010196634
	oxytetracycline Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.026199682
	Afatinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.00612757
	CCMQ Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.009034787
	Itopride Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.0029835387
	Narciclasine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.019885236
	FCCP Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.050812725
	1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.0040192916
	N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	0.008882821
	alpelisib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TRIB3 Gene (Entity type)	-0.0038829362

Tioguanine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.010196634

oxytetracycline
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.026199682

Afatinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.00612757

CCMQ
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.009034787

Itopride
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.0029835387

Narciclasine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.019885236

FCCP
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.050812725

1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N(3)-((S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzocyclohepten-2-yl)-1H-[1,2,4]triazole-3,5-diamine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.0040192916

N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
0.008882821

alpelisib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TRIB3
Gene (Entity type)
-0.0038829362

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.