(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CD200 Gene (Entity type)	0.0058025797
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HSPB8 Gene (Entity type)	-0.008549546
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLSCR4 Gene (Entity type)	0.006450484
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A5 Gene (Entity type)	-0.007480742
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PI-103 Compound (Entity type)	0.7369379997253418
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AKR1C1 Gene (Entity type)	-0.00836186
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDKN1A Gene (Entity type)	-0.006826351
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SPARC Gene (Entity type)	0.006623355
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.007255287
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	RAC-gamma serine/threonine-protein kinase Protein (Entity type)	IC50

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CD200
Gene (Entity type)
0.0058025797

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HSPB8
Gene (Entity type)
-0.008549546

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLSCR4
Gene (Entity type)
0.006450484

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC7A5
Gene (Entity type)
-0.007480742

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PI-103
Compound (Entity type)
0.7369379997253418

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AKR1C1
Gene (Entity type)
-0.00836186

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDKN1A
Gene (Entity type)
-0.006826351

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SPARC
Gene (Entity type)
0.006623355

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.007255287

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
RAC-gamma serine/threonine-protein kinase
Protein (Entity type)
IC50

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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