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PI-103 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PI-103's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	PI-103 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SLC7A5 Gene (Entity type)	-0.006880671
	PI-103 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	STC2 Gene (Entity type)	-0.0063613523
	PI-103 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	YARS1 Gene (Entity type)	-0.006831869
	PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	0.0060323197
	(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	PI-103 Compound (Entity type)	0.7369379997253418
	PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IRS2 Gene (Entity type)	0.009297715
	PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CCN2 Gene (Entity type)	0.0064982
	PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDKN1B Gene (Entity type)	0.005785308
	PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.0057441434
	PI-103 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	-0.008743187

PI-103
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SLC7A5
Gene (Entity type)
-0.006880671

PI-103
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
STC2
Gene (Entity type)
-0.0063613523

PI-103
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
YARS1
Gene (Entity type)
-0.006831869

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
0.0060323197

(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
PI-103
Compound (Entity type)
0.7369379997253418

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IRS2
Gene (Entity type)
0.009297715

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CCN2
Gene (Entity type)
0.0064982

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDKN1B
Gene (Entity type)
0.005785308

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGF1R
Gene (Entity type)
0.0057441434

PI-103
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
-0.008743187

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