Information PortalData PortalKnowledge Portal

Data Matrix

Tools & Workflows

Documentation

LETMD1 (Gene)

Ensembl Gene ID: ENSG00000050426

Entrez Gene ID: 25875

Description: LETM1 domain containing 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View LETMD1's neighborhood in the knowledge graph.

Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with LETMD1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using LETMD1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for LETMD1.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LETMD1.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

This repository is under review for potential modification in compliance with Administration directives.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.013146974
	staurosporine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.008229016
	pralatrexate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.013592115
	1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.0055169347
	AZD-2014::CHEMBL2336325::US9102670, 1ap Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.010743288
	5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.016626116
	Lestaurtinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.009357949
	KFGENEBIN:LETMD1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)
	dactolisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.011415294
	BGT-226 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LETMD1 Gene (Entity type)	0.014360697

9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.013146974

staurosporine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.008229016

pralatrexate
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.013592115

1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.0055169347

AZD-2014::CHEMBL2336325::US9102670, 1ap
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.010743288

5-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzo[d]oxazol-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.016626116

Lestaurtinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.009357949

KFGENEBIN:LETMD1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)

dactolisib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.011415294

BGT-226
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LETMD1
Gene (Entity type)
0.014360697

DISPLAY PER PAGE