BGT-226 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BGT-226's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
BGT-226 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.011090265
BGT-226 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EIF3D Gene (Entity type)	0.011474068
BGT-226 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.7239861488342285
BGT-226 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein (Entity type)	IC50
BGT-226 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea Compound (Entity type)	0.7316129207611084
BGT-226 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EBP Gene (Entity type)	-0.012301753
BGT-226 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase mTOR Protein (Entity type)	IC50
BGT-226 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LMNB1 Gene (Entity type)	-0.012416266
BGT-226 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABCC3 Gene (Entity type)	0.012494846
BGT-226 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PPP1R3C Gene (Entity type)	-0.013489058

BGT-226
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.011090265

BGT-226
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EIF3D
Gene (Entity type)
0.011474068

BGT-226
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.7239861488342285

BGT-226
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein (Entity type)
IC50

BGT-226
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea
Compound (Entity type)
0.7316129207611084

BGT-226
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EBP
Gene (Entity type)
-0.012301753

BGT-226
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase mTOR
Protein (Entity type)
IC50

BGT-226
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LMNB1
Gene (Entity type)
-0.012416266

BGT-226
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABCC3
Gene (Entity type)
0.012494846

BGT-226
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PPP1R3C
Gene (Entity type)
-0.013489058

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Knowledge Graph Assertions

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