AMIGO2 (Gene)

Entrez Gene ID: 347902

Description: adhesion molecule with Ig like domain 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AMIGO2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AMIGO2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AMIGO2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AMIGO2.

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Gene Sets (7090)

LINCS L1000 Chem Pert Consensus Sigs (1927)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (4)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1854)

A gene set library provided by LINCS

rummageo gene perturbations (233)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (2641)

A gene set library provided by LINCS

rummageo chemical perturbations (415)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (12)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
meptazinol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.0053561954
SA-440832 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.016134368
2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.0053979275
itdac-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.019291056
BCL2-inhibitor Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.008759578
BGT-226 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.011090265
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.0062042703
Primaquine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	0.0073408936
Celiprolol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.020287003
Piclamilast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	AMIGO2 Gene (Entity type)	-0.0034680117

meptazinol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.0053561954

SA-440832
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.016134368

2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrrolo[1,2-e]imidazol-2(3H)-yl)-3-methylbenzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.0053979275

itdac-1
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.019291056

BCL2-inhibitor
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.008759578

BGT-226
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.011090265

1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.0062042703

Primaquine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
0.0073408936

Celiprolol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.020287003

Piclamilast
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
AMIGO2
Gene (Entity type)
-0.0034680117

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.