(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	-0.01979006
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MET Gene (Entity type)	0.011813464
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GARS1 Gene (Entity type)	-0.012972857
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARG2 Gene (Entity type)	-0.012901645
BGT-226 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.7239861488342285
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	-0.017396035
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC25A6 Gene (Entity type)	0.011225745
OSI-027 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	0.8613381385803223
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one Compound (Entity type)	0.8778050541877747
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DHCR7 Gene (Entity type)	-0.014813661

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
-0.01979006

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MET
Gene (Entity type)
0.011813464

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GARS1
Gene (Entity type)
-0.012972857

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ARG2
Gene (Entity type)
-0.012901645

BGT-226
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.7239861488342285

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
-0.017396035

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC25A6
Gene (Entity type)
0.011225745

OSI-027
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
0.8613381385803223

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
Compound (Entity type)
0.8778050541877747

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DHCR7
Gene (Entity type)
-0.014813661

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Knowledge Graph Assertions

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