ORAI3 (Gene)

Description: ORAI calcium release-activated calcium modulator 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ORAI3's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ORAI3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ORAI3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ORAI3.

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Gene Sets (404)

LINCS L1000 Chem Pert Consensus Sigs (323)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (76)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
wortmannin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.005626963
PP-110 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.011532755
KFGENEBIN:ORAI3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)
BMS-345541 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	-0.0050114114
4-[(S)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(4-methyl-6-morpholin-4-yl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.0069215223
TAK-733 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.010736657
N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	-0.003770589
1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.005757426
PP-30 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.011207423
Efatutazone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	-0.007332047