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TAK-733 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TAK-733's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	cobimetinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TAK-733 Compound (Entity type)	0.80135178565979
	TAK-733 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL13RA2 Gene (Entity type)	-0.011282346
	VS-4718 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	TAK-733 Compound (Entity type)	0.5021581649780273
	TAK-733 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MVP Gene (Entity type)	0.010985672
	TAK-733 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NUPR1 Gene (Entity type)	0.014253863
	TAK-733 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	POLE2 Gene (Entity type)	-0.0127639165
	TAK-733 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL1 Gene (Entity type)	-0.012493035
	TAK-733 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IL32 Gene (Entity type)	0.012330362
	TAK-733 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPB1 Gene (Entity type)	0.012087904
	TAK-733 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	binimetinib Compound (Entity type)	0.8071167469024658

cobimetinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TAK-733
Compound (Entity type)
0.80135178565979

TAK-733
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL13RA2
Gene (Entity type)
-0.011282346

VS-4718
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
TAK-733
Compound (Entity type)
0.5021581649780273

TAK-733
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MVP
Gene (Entity type)
0.010985672

TAK-733
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NUPR1
Gene (Entity type)
0.014253863

TAK-733
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
POLE2
Gene (Entity type)
-0.0127639165

TAK-733
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL1
Gene (Entity type)
-0.012493035

TAK-733
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IL32
Gene (Entity type)
0.012330362

TAK-733
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HSPB1
Gene (Entity type)
0.012087904

TAK-733
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
binimetinib
Compound (Entity type)
0.8071167469024658

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