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binimetinib (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View binimetinib's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	binimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	YKT6 Gene (Entity type)	-0.008296747
	VS-4718 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	binimetinib Compound (Entity type)	0.4394751787185669
	binimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	0.01406225
	binimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AKR1C3 Gene (Entity type)	0.010899933
	binimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CAPN1 Gene (Entity type)	0.012444618
	binimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IL13RA2 Gene (Entity type)	-0.008575398
	binimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MX1 Gene (Entity type)	0.011363351
	binimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KIF14 Gene (Entity type)	-0.008480636
	binimetinib Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Ro-4987655 Compound (Entity type)	0.8324711918830872
	binimetinib Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ETV1 Gene (Entity type)	-0.00918237

binimetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
YKT6
Gene (Entity type)
-0.008296747

VS-4718
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
binimetinib
Compound (Entity type)
0.4394751787185669

binimetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CFB
Gene (Entity type)
0.01406225

binimetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AKR1C3
Gene (Entity type)
0.010899933

binimetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CAPN1
Gene (Entity type)
0.012444618

binimetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IL13RA2
Gene (Entity type)
-0.008575398

binimetinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MX1
Gene (Entity type)
0.011363351

binimetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KIF14
Gene (Entity type)
-0.008480636

binimetinib
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Ro-4987655
Compound (Entity type)
0.8324711918830872

binimetinib
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ETV1
Gene (Entity type)
-0.00918237

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