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wortmannin (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View wortmannin's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	wortmannin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ORAI3 Gene (Entity type)	0.005626963
	wortmannin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	0.6895558834075928
	wortmannin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Serine/threonine-protein kinase PLK1 Protein (Entity type)	IC50
	wortmannin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Protein (Entity type)	IC50
	wortmannin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.005238682
	4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)-2-methoxybenzoic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	wortmannin Compound (Entity type)	0.4818400740623474
	JW-7-24-1 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	wortmannin Compound (Entity type)	0.4519369602203369
	wortmannin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	-0.005255729
	wortmannin Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Heat shock protein HSP 90-alpha Protein (Entity type)	AC50
	wortmannin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	UBE2S Gene (Entity type)	-0.0055892523

wortmannin
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ORAI3
Gene (Entity type)
0.005626963

wortmannin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
0.6895558834075928

wortmannin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Serine/threonine-protein kinase PLK1
Protein (Entity type)
IC50

wortmannin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein (Entity type)
IC50

wortmannin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IDH3A
Gene (Entity type)
-0.005238682

4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[e]pyrimido[5,4-c]azepin-2-ylamino)-2-methoxybenzoic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
wortmannin
Compound (Entity type)
0.4818400740623474

JW-7-24-1
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
wortmannin
Compound (Entity type)
0.4519369602203369

wortmannin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
-0.005255729

wortmannin
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Heat shock protein HSP 90-alpha
Protein (Entity type)
AC50

wortmannin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
UBE2S
Gene (Entity type)
-0.0055892523

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