2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
wortmannin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	0.6895558834075928
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MARCKSL1 Gene (Entity type)	0.0051714163
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOXO4 Gene (Entity type)	0.0052625495
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF83 Gene (Entity type)	0.005140952
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NIBAN1 Gene (Entity type)	-0.005500514
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ATP9A Gene (Entity type)	0.0054876204
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.005050963
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	WDTC1 Gene (Entity type)	0.0053600892
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BTG3 Gene (Entity type)	-0.006025306
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SLC35E2B Gene (Entity type)	0.0053100036

wortmannin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
0.6895558834075928

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MARCKSL1
Gene (Entity type)
0.0051714163

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOXO4
Gene (Entity type)
0.0052625495

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF83
Gene (Entity type)
0.005140952

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NIBAN1
Gene (Entity type)
-0.005500514

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ATP9A
Gene (Entity type)
0.0054876204

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOP53
Gene (Entity type)
0.005050963

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
WDTC1
Gene (Entity type)
0.0053600892

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BTG3
Gene (Entity type)
-0.006025306

2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SLC35E2B
Gene (Entity type)
0.0053100036

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