IDH3A (Gene)

Description: isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IDH3A's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IDH3A.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IDH3A.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IDH3A.

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Gene Sets (475)

LINCS L1000 Chem Pert Consensus Sigs (338)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (125)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (2)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
terfenadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.008960209
wortmannin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.005238682
IDH3A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nadide Metabolite (Entity type)
IDH3A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	2-oxopentanedioic acid Metabolite (Entity type)
BG-1024 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.022139065
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.0107128825
IDH3A Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	nicotinamide adenine dinucleotide (NAD) Metabolite (Entity type)
Deforolimus Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.011566519
SID11113879 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	0.0045852996
PF-04691502 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.008590018