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terfenadine (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View terfenadine's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	K-788-2192 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	terfenadine Compound (Entity type)	0.2921053469181061
	terfenadine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	0.031310834
	KU-C103904N Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	terfenadine Compound (Entity type)	0.2695374488830566
	terfenadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MAGEA3 Gene (Entity type)	-0.008634472
	[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	terfenadine Compound (Entity type)	0.5842692255973816
	GBR-13069 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	terfenadine Compound (Entity type)	0.4058848917484283
	terfenadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ENC1 Gene (Entity type)	-0.009075399
	terfenadine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CYP51A1 Gene (Entity type)	0.015805012
	terfenadine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IDH3A Gene (Entity type)	-0.008960209
	terfenadine Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Potassium voltage-gated channel subfamily H member 2 Protein (Entity type)	IC50

K-788-2192
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
terfenadine
Compound (Entity type)
0.2921053469181061

terfenadine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
0.031310834

KU-C103904N
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
terfenadine
Compound (Entity type)
0.2695374488830566

terfenadine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MAGEA3
Gene (Entity type)
-0.008634472

[6-Hydroxy-2-(4-hydroxy-phenyl)-benzo[b]thiophen-3-yl]-[4-(4-isopropyl-piperazin-1-yl)-phenyl]-methanone
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
terfenadine
Compound (Entity type)
0.5842692255973816

GBR-13069
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
terfenadine
Compound (Entity type)
0.4058848917484283

terfenadine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ENC1
Gene (Entity type)
-0.009075399

terfenadine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CYP51A1
Gene (Entity type)
0.015805012

terfenadine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IDH3A
Gene (Entity type)
-0.008960209

terfenadine
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Potassium voltage-gated channel subfamily H member 2
Protein (Entity type)
IC50

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