2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FDPS Gene (Entity type)	0.017670644
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	5-hydroxytryptamine receptor 6 Protein (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TEX10 Gene (Entity type)	-0.0100656655
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [3-(2-dimethylamino-ethoxy)-4-methoxy-phenyl]-amide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	0.56056147813797
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	P3H2 Gene (Entity type)	-0.013363545
SID11111874 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	0.3746342658996582
Bietaserpine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	0.2390724420547485
apilimod Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	0.6491381525993347
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CDC45 Gene (Entity type)	-0.009318051
Perhexiline Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide Compound (Entity type)	0.5689892172813416

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FDPS
Gene (Entity type)
0.017670644

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
5-hydroxytryptamine receptor 6
Protein (Entity type)

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TEX10
Gene (Entity type)
-0.0100656655

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [3-(2-dimethylamino-ethoxy)-4-methoxy-phenyl]-amide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
0.56056147813797

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
P3H2
Gene (Entity type)
-0.013363545

SID11111874
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
0.3746342658996582

Bietaserpine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
0.2390724420547485

apilimod
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
0.6491381525993347

2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CDC45
Gene (Entity type)
-0.009318051

Perhexiline
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2'-Methyl-4'-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide
Compound (Entity type)
0.5689892172813416

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