2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine's neighborhood in the knowledge graph.

Submit

Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FOXO4 Gene (Entity type)	0.005511634
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBP1 Gene (Entity type)	0.0046318937
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TMT1A Gene (Entity type)	0.004988321
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	DNAJB1 Gene (Entity type)	-0.0029505072
TGX-115 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	0.5088358521461487
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	KRT19 Gene (Entity type)	-0.0029388708
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	JMJD6 Gene (Entity type)	-0.0032017818
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PNRC1 Gene (Entity type)	0.0038686679
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ADM Gene (Entity type)	-0.0035566424
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	DUSP6 Gene (Entity type)	0.006129969

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FOXO4
Gene (Entity type)
0.005511634

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBP1
Gene (Entity type)
0.0046318937

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TMT1A
Gene (Entity type)
0.004988321

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
DNAJB1
Gene (Entity type)
-0.0029505072

TGX-115
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
0.5088358521461487

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
KRT19
Gene (Entity type)
-0.0029388708

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
JMJD6
Gene (Entity type)
-0.0032017818

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PNRC1
Gene (Entity type)
0.0038686679

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ADM
Gene (Entity type)
-0.0035566424

2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
DUSP6
Gene (Entity type)
0.006129969

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Knowledge Graph Assertions

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