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TGX-115 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TGX-115's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	TGX-115 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	0.008291491
	TGX-115 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMOX1 Gene (Entity type)	-0.016248873
	TGX-115 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ASPM Gene (Entity type)	0.009585909
	TGX-115 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MEIS2 Gene (Entity type)	-0.011248141
	TGX-115 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	0.5088358521461487
	TGX-115 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HBP1 Gene (Entity type)	0.009380563
	TGX-115 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	GPNMB Gene (Entity type)	-0.011250818
	TGX-115 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	-0.012812003
	TGX-115 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	BMS-754807 Compound (Entity type)	0.5123088359832764
	TGX-115 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HMGCS1 Gene (Entity type)	-0.014876734

TGX-115
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM5D
Gene (Entity type)
0.008291491

TGX-115
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMOX1
Gene (Entity type)
-0.016248873

TGX-115
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ASPM
Gene (Entity type)
0.009585909

TGX-115
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MEIS2
Gene (Entity type)
-0.011248141

TGX-115
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine
Compound (Entity type)
0.5088358521461487

TGX-115
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HBP1
Gene (Entity type)
0.009380563

TGX-115
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
GPNMB
Gene (Entity type)
-0.011250818

TGX-115
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
-0.012812003

TGX-115
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
BMS-754807
Compound (Entity type)
0.5123088359832764

TGX-115
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HMGCS1
Gene (Entity type)
-0.014876734

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