VX-680/MK-0457 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View VX-680/MK-0457's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CENPE Gene (Entity type)	0.0048999214
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	INSIG1 Gene (Entity type)	0.005437281
VX-680/MK-0457 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EIF5A Gene (Entity type)	-0.005501057
VX-680/MK-0457 Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Uncharacterized protein FLJ45252 Protein (Entity type)	Kd
VX-680/MK-0457 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SIK1 Gene (Entity type)	-0.0031162119
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCD Gene (Entity type)	0.005387859
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.0045307376
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QPRT Gene (Entity type)	0.0051443726
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.005441213
VX-680/MK-0457 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RGS4 Gene (Entity type)	-0.0032448797

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CENPE
Gene (Entity type)
0.0048999214

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
INSIG1
Gene (Entity type)
0.005437281

VX-680/MK-0457
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
EIF5A
Gene (Entity type)
-0.005501057

VX-680/MK-0457
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Uncharacterized protein FLJ45252
Protein (Entity type)
Kd

VX-680/MK-0457
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SIK1
Gene (Entity type)
-0.0031162119

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCD
Gene (Entity type)
0.005387859

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.0045307376

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QPRT
Gene (Entity type)
0.0051443726

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.005441213

VX-680/MK-0457
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RGS4
Gene (Entity type)
-0.0032448797

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Knowledge Graph Assertions

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