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CFDE Workbench

CENPE (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:CENP-E, CENPE, ENTREZ:1062, HGNC:1856, KIF10, MCPH13, MIM:117143, NM_001286734, NM_001813, NP_001273663, NP_001804, PPP1R61, XM_011531544, XM_011531545, XM_011531546, XM_011531547, XM_011531548, XM_011531549, XM_017007659, XP_011529846, XP_011529847, XP_011529848, XP_011529849, XP_011529850, XP_011529851, XP_016863148, centromere protein E
Omim:OMIM:117143
Id:ENSG00000138778
Hgnc:HGNC:1856
Entrez:1062
Ensembl:ENSG00000138778
Description:centromere protein E
Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]

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Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CENPE's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CENPE.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CENPE.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CENPE.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CENPE.

Results found

Linked to

 

Label

Description

 

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A Gene Set from LINCS

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GSE193993 SSTR2 knockout 0 v 2 human up

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A Gene Set from LINCS

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GSE239844 crizotinib 11 v 9 human dn

Gene Set (Entity type)

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GSE213588 trametinib NF1 8 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 trametinib NF1 8 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193993 SSTR2 knockout 1 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE171837 0 V 1 BORTEZOMIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE164874 prednisolone muscle organ 5 v 9 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE171837 bortezomib 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE214505 AKR1B1 knockdown A-549 3 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE226525 GSE226527 HNRNPH2 knockout 4 v 8 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 0 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE239844 crizotinib 11 v 9 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 8 v 7 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 trametinib NF1 8 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 1 v 7 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE171837 0 V 1 BORTEZOMIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE164874 prednisolone muscle organ 5 v 9 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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