SQLE (Gene)

Entrez Gene ID: 6713

Description: squalene epoxidase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SQLE's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SQLE.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SQLE.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SQLE.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SQLE.

Gene Sets (4531)

LINCS L1000 Chem Pert Consensus Sigs (1254)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (1)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (481)

A gene set library provided by LINCS

rummageo gene perturbations (285)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (647)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (1388)

A gene set library provided by LINCS

rummageo chemical perturbations (469)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (2)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
iloperidone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.012638847
Imperatorin Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	-0.010953933
SID11113504 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	-0.03473008
SID11113772 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.022399861
GSK269962A Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	-0.009246709
BMS-833923 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.01316738
Fluoxetine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.007643284
Pirlindole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.004159277
SA-1921456 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.017978776
Ceritinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SQLE Gene (Entity type)	0.010263591

iloperidone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.012638847

Imperatorin
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
-0.010953933

SID11113504
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
-0.03473008

SID11113772
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.022399861

GSK269962A
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
-0.009246709

BMS-833923
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.01316738

Fluoxetine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.007643284

Pirlindole
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.004159277

SA-1921456
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.017978776

Ceritinib
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SQLE
Gene (Entity type)
0.010263591

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Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.