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RPS27L (Gene)

Ensembl Gene ID: ENSG00000185088

Entrez Gene ID: 51065

Description: ribosomal protein S27 like

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View RPS27L's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RPS27L.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using RPS27L.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for RPS27L.

Gene Sets (2452)

LINCS L1000 Chem Pert Consensus Sigs (615)

A gene set library provided by LINCS

LINCS L1000 CRISPR KO Consensus Sigs (746)

A gene set library provided by LINCS

rummageo gene perturbations (179)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (661)

A gene set library provided by LINCS

rummageo chemical perturbations (250)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	(S)-4,11-Diethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.015657736
	3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	-0.0035105457
	N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	-0.003836159
	(8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.0051796334
	Carbamazepine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	-0.0038623828
	Mepivacaine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	-0.0067812526
	[1,4']Bipiperidinyl-1'-carboxylic acid (S)-4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-yl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.007851669
	Selinexor Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.011865041
	VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.0045307376
	mycophenolate-mofetil Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RPS27L Gene (Entity type)	0.01036575

(S)-4,11-Diethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.015657736

3-(6-(4-(trifluoromethoxy)phenylamino)pyrimidin-4-yl)benzamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
-0.0035105457

N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
-0.003836159

(8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.0051796334

Carbamazepine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
-0.0038623828

Mepivacaine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
-0.0067812526

[1,4']Bipiperidinyl-1'-carboxylic acid (S)-4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-yl ester
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.007851669

Selinexor
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.011865041

VX-680/MK-0457
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.0045307376

mycophenolate-mofetil
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RPS27L
Gene (Entity type)
0.01036575

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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