BIK (Gene)

Description: BCL2 interacting killer

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BIK's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with BIK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using BIK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for BIK.

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Gene Sets (2033)

LINCS L1000 Chem Pert Consensus Sigs (860)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (3)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (1158)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (4)

A gene set library provided by GTEx

GTEx Tissues V8 2023 (8)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
ethyl-pyruvate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.0065367837
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.004026216
Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.02461673
Guanadrel Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	0.0026859788
Methoxyflurane Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	0.0047759423
Ioversol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	0.01806647
SA-89210 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.0066299005
JAS07-004 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.01038421
1-Phenyl-cyclopentanecarboxylic acid 2-(2-diethylamino-ethoxy)-ethyl ester Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	0.012752771
SA-243913 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	0.01167771