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Efaroxan (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Efaroxan's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGFBP2 Gene (Entity type)	-0.025130404
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.02461673
	Efaroxan Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	(S)-1-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide Compound (Entity type)	0.2565198838710785
	Efaroxan Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Alpha-2A adrenergic receptor Protein (Entity type)	Ki
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IFITM1 Gene (Entity type)	-0.02998756
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TSPAN4 Gene (Entity type)	-0.024687456
	Efaroxan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SCPEP1 Gene (Entity type)	0.02420463
	Efaroxan Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PDGFC Gene (Entity type)	0.03084499
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	RFTN1 Gene (Entity type)	-0.0297169
	Efaroxan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP9 Gene (Entity type)	-0.034512684

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IGFBP2
Gene (Entity type)
-0.025130404

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BIK
Gene (Entity type)
-0.02461673

Efaroxan
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
(S)-1-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide
Compound (Entity type)
0.2565198838710785

Efaroxan
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Alpha-2A adrenergic receptor
Protein (Entity type)
Ki

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
IFITM1
Gene (Entity type)
-0.02998756

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TSPAN4
Gene (Entity type)
-0.024687456

Efaroxan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SCPEP1
Gene (Entity type)
0.02420463

Efaroxan
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PDGFC
Gene (Entity type)
0.03084499

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
RFTN1
Gene (Entity type)
-0.0297169

Efaroxan
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP9
Gene (Entity type)
-0.034512684

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