2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BIK Gene (Entity type)	-0.004026216
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	0.0041673766
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CPD Gene (Entity type)	-0.0036065995
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TPD52L1 Gene (Entity type)	-0.0040771198
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	FSTL1 Gene (Entity type)	0.003960961
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Dihydroorotate dehydrogenase Protein (Entity type)	IC50
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AQP3 Gene (Entity type)	0.0059321243
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	METRN Gene (Entity type)	0.005911003
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IL7R Gene (Entity type)	0.0038040131
2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	RGS5 Gene (Entity type)	0.0041393396

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BIK
Gene (Entity type)
-0.004026216

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
0.0041673766

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CPD
Gene (Entity type)
-0.0036065995

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TPD52L1
Gene (Entity type)
-0.0040771198

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
FSTL1
Gene (Entity type)
0.003960961

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Dihydroorotate dehydrogenase
Protein (Entity type)
IC50

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AQP3
Gene (Entity type)
0.0059321243

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
METRN
Gene (Entity type)
0.005911003

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IL7R
Gene (Entity type)
0.0038040131

2-(3-Fluoro-3'-methoxy-biphenyl-4-ylcarbamoyl)-cyclopent-1-enecarboxylic acid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
RGS5
Gene (Entity type)
0.0041393396

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