CFB (Gene)

Description: complement factor B

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CFB's neighborhood in the knowledge graph.

Submit

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CFB.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CFB.

Submit

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CFB.

Submit

Gene Sets (3122)

LINCS L1000 Chem Pert Consensus Sigs (1523)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (13)

A gene set library provided by GlyGen

KOMP2 Mouse Phenotypes 2022 (7)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (1565)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (1)

A gene set library provided by GTEx

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

GTEx Tissues V8 2023 (6)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
N-hydroxy-7-oxo-7-(2-(4-(pyridin-4-yl)benzylidene)hydrazinyl)heptanamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.017167976
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	0.009922392
SID11111610 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.009228549
1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.0045624115
ungerine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.009714132
(4-benzylpiperazino)acetic acid(3-allyl-2-hydroxybenzylidene)hydrazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.0074646873
clomethiazole Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.003728193
binimetinib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	0.01406225
immepip Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	0.013070891
(3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphosphonic acid Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	-0.009590597