[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View [3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat)'s neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ARG1 Gene (Entity type)	0.008780501
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CFB Gene (Entity type)	0.009922392
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.010214901
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CLIC4 Gene (Entity type)	-0.009871652
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PERP Gene (Entity type)	-0.009874801
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GZMA Gene (Entity type)	0.01288685
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PSMB9 Gene (Entity type)	0.00865134
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PRAME Gene (Entity type)	-0.010740606
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IFRD2 Gene (Entity type)	0.009834143
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HSPB8 Gene (Entity type)	0.009588438