IGF1R (Gene)

Description: insulin like growth factor 1 receptor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View IGF1R's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IGF1R.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using IGF1R.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for IGF1R.

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Gene Sets (725)

LINCS L1000 Chem Pert Consensus Sigs (301)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (1)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (412)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

IDG Drug Targets 2022 (9)

A gene set library provided by IDG

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KFGENEBIN:IGF1R-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)
Isradipine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	-0.003212993
PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.0057441434
GSK2334470 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.005809365
T-5345967 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.0058147986
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.012960671
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.012285303
YC-1 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	-0.008604083
PIK-90 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	0.012028852
COT-10b Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	IGF1R Gene (Entity type)	-0.011308499