NOTCH2 (Gene)

Description: notch receptor 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NOTCH2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NOTCH2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NOTCH2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NOTCH2.

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Gene Sets (85822)

LINCS L1000 Chem Pert Consensus Sigs (688)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (5)

A gene set library provided by MoTrPAC

LINCS L1000 CRISPR KO Consensus Sigs (787)

A gene set library provided by LINCS

l1000 cp (83049)

A gene set library provided by LINCS

rummageo gene perturbations (211)

A gene set library provided by LINCS

rummageo chemical perturbations (291)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

GlyGen Glycosylated Proteins 2022 (3)

A gene set library provided by GlyGen

LINCS L1000 Consensus Median Signatures (783)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Nomifensine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.0095794145
hydrocotarnine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	-0.0095693115
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.0040037306
2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester (Yohimbine) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	-0.0034158563
Gimeracil Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	-0.0058629992
zosuquidar Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	-0.0029218777
choline-alfoscerate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.0038254142
Felbinac Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.004289664
KFGENEBIN:NOTCH2-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)
Enzalutamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.0035227155