2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Equilibrative nucleoside transporter 1 Protein (Entity type)	Ki
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CIAO3 Gene (Entity type)	-0.003528218
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	VCAM1 Gene (Entity type)	-0.0037340806
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PSAT1 Gene (Entity type)	0.003853968
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOTCH2 Gene (Entity type)	0.0040037306
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AHCYL1 Gene (Entity type)	0.0041049193
(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	0.4773869216442108
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	TEX10 Gene (Entity type)	-0.0034469762
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CHN1 Gene (Entity type)	0.0043267165
radezolid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide Compound (Entity type)	0.2947627007961273

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Equilibrative nucleoside transporter 1
Protein (Entity type)
Ki

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CIAO3
Gene (Entity type)
-0.003528218

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
VCAM1
Gene (Entity type)
-0.0037340806

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PSAT1
Gene (Entity type)
0.003853968

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
NOTCH2
Gene (Entity type)
0.0040037306

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AHCYL1
Gene (Entity type)
0.0041049193

(R)-1-(2-bromophenyl)-3-(1-(5-(trifluoromethyl)pyridin-2-yl)pyrrolidin-3-yl)urea
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
0.4773869216442108

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
TEX10
Gene (Entity type)
-0.0034469762

2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CHN1
Gene (Entity type)
0.0043267165

radezolid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
Compound (Entity type)
0.2947627007961273

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