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Enzalutamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Enzalutamide's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Enzalutamide Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Androgen receptor Protein (Entity type)	IC50
	N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Enzalutamide Compound (Entity type)	0.356507271528244
	Enzalutamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	INHBB Gene (Entity type)	-0.0034309793
	Enzalutamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SCGB2A2 Gene (Entity type)	-0.0038272105
	SA-424763 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Enzalutamide Compound (Entity type)	0.2588048875331878
	Enzalutamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KDM5D Gene (Entity type)	0.0032563638
	thiazolopyrimidine Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Enzalutamide Compound (Entity type)	0.5065053701400757
	Enzalutamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	SID11113346 Compound (Entity type)	0.4377787411212921
	Enzalutamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SERPINB2 Gene (Entity type)	0.004189496
	Enzalutamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MCM3 Gene (Entity type)	0.0031783183

Enzalutamide
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Androgen receptor
Protein (Entity type)
IC50

N-(2,4-Di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Enzalutamide
Compound (Entity type)
0.356507271528244

Enzalutamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
INHBB
Gene (Entity type)
-0.0034309793

Enzalutamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SCGB2A2
Gene (Entity type)
-0.0038272105

SA-424763
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Enzalutamide
Compound (Entity type)
0.2588048875331878

Enzalutamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KDM5D
Gene (Entity type)
0.0032563638

thiazolopyrimidine
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Enzalutamide
Compound (Entity type)
0.5065053701400757

Enzalutamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
SID11113346
Compound (Entity type)
0.4377787411212921

Enzalutamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SERPINB2
Gene (Entity type)
0.004189496

Enzalutamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MCM3
Gene (Entity type)
0.0031783183

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