QARS1 (Gene)

Ensembl Gene ID: ENSG00000172053

Entrez Gene ID: 5859

Description: glutaminyl-tRNA synthetase 1

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View QARS1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with QARS1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using QARS1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for QARS1.

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Gene Sets (484)

rummageo gene perturbations (155)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (118)

A gene set library provided by LINCS

rummageo chemical perturbations (211)

A gene set library provided by LINCS

Knowledge Graph Assertions

Source	Relation	Target	Evidence
GSK-1059615 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.006852905
QARS1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	adenosine monophosphate Metabolite (Entity type)
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.011636989
PF-04691502 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.009463991
5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.0086734295
QARS1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	atp binding Metabolite (Entity type)
QARS1 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	ATP Metabolite (Entity type)
(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.011991916
AZD-2014::CHEMBL2336325::US9102670, 1ap Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.009429062
PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	QARS1 Gene (Entity type)	0.005864224

GSK-1059615
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.006852905

QARS1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
adenosine monophosphate
Metabolite (Entity type)

(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.011636989

PF-04691502
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.009463991

5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.0086734295

QARS1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
atp binding
Metabolite (Entity type)

QARS1
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
ATP
Metabolite (Entity type)

(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.011991916

AZD-2014::CHEMBL2336325::US9102670, 1ap
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.009429062

PI-103
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
QARS1
Gene (Entity type)
0.005864224

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.