AMPD3 (Gene)

Entrez Gene ID: 272

Description: adenosine monophosphate deaminase 3

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View AMPD3's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with AMPD3.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using AMPD3.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for AMPD3.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with AMPD3.

Gene Sets (1837)

LINCS L1000 Chem Pert Consensus Sigs (299)

A gene set library provided by LINCS

Metabolomics Workbench Metabolites 2022 (2)

A gene set library provided by MW

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (6)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (194)

A gene set library provided by LINCS

rummageo gene perturbations (187)

A gene set library provided by LINCS

RummaGEO DrugPerturbations 2025 (492)

A gene set library provided by LINCS

LINCS L1000 Consensus Median Signatures (377)

A gene set library provided by LINCS

rummageo chemical perturbations (274)

A gene set library provided by LINCS

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
AMPD3 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate Metabolite (Entity type)
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMPD3 Gene (Entity type)	0.0041745217
AMPD3 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	Inosine Monophosphate Metabolite (Entity type)
N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMPD3 Gene (Entity type)	0.00623505
AMPD3 Gene (Entity type)	Causally influences Knowledge Graph Relation (Entity type)	adenosine monophosphate Metabolite (Entity type)
Entacapone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	AMPD3 Gene (Entity type)	0.008694792
KFGENEBIN:AMPD3-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	AMPD3 Gene (Entity type)

AMPD3
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate
Metabolite (Entity type)

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMPD3
Gene (Entity type)
0.0041745217

AMPD3
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
Inosine Monophosphate
Metabolite (Entity type)

N-{4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl}-N'-(3-fluoro-2-methylphenyl)urea
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMPD3
Gene (Entity type)
0.00623505

AMPD3
Gene (Entity type)
Causally influences
Knowledge Graph Relation (Entity type)
adenosine monophosphate
Metabolite (Entity type)

Entacapone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
AMPD3
Gene (Entity type)
0.008694792

KFGENEBIN:AMPD3-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
AMPD3
Gene (Entity type)

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Knowledge Graph Assertions

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@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.