4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NUP85 Gene (Entity type)	-0.004538508
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KRT7 Gene (Entity type)	0.004042178
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PLAAT3 Gene (Entity type)	-0.0041340766
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LTF Gene (Entity type)	0.006749192
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ITM2C Gene (Entity type)	-0.0050303712
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPINK1 Gene (Entity type)	-0.004727481
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SRGN Gene (Entity type)	-0.0035213297
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	HPGD Gene (Entity type)	-0.004071549
Oxybutynin Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	0.3776619434356689
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	JCHAIN Gene (Entity type)	-0.0043648123

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NUP85
Gene (Entity type)
-0.004538508

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KRT7
Gene (Entity type)
0.004042178

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
PLAAT3
Gene (Entity type)
-0.0041340766

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LTF
Gene (Entity type)
0.006749192

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ITM2C
Gene (Entity type)
-0.0050303712

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPINK1
Gene (Entity type)
-0.004727481

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SRGN
Gene (Entity type)
-0.0035213297

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
HPGD
Gene (Entity type)
-0.004071549

Oxybutynin
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
0.3776619434356689

4-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
JCHAIN
Gene (Entity type)
-0.0043648123

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