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ABCB1 (Gene)

Ensembl Gene ID: ENSG00000085563

Entrez Gene ID: 5243

Description: ATP binding cassette subfamily B member 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ABCB1's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ABCB1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ABCB1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ABCB1.

Gene Sets (2174)

LINCS L1000 Chem Pert Consensus Sigs (458)

A gene set library provided by LINCS

Illuminating the Druggable Genome

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (472)

A gene set library provided by LINCS

rummageo gene perturbations (171)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (2)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (748)

A gene set library provided by LINCS

rummageo chemical perturbations (233)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Tissues V8 2023 (11)

A gene set library provided by GTEx

Illuminating the Druggable Genome

IDG Drug Targets 2022 (77)

A gene set library provided by IDG

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Zidovudine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)	0.0040981425
	docebenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)	-0.03231609
	ORG-9768 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)	0.003670856
	KFGENEBIN:ABCB1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)
	1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole)::1-(biphenyl-4-yl-phenyl-methyl)-1H-imidazole::BIFONAZOLE::CHEMBL277535::US9144538, Bifonazole::cid_2378 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)	-0.004072682
	Endothelial cell of venule Anatomy (Entity type)	Has marker gene in heart Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)
	rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ABCB1 Gene (Entity type)	-0.0033512197

Zidovudine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)
0.0040981425

docebenone
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)
-0.03231609

ORG-9768
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)
0.003670856

KFGENEBIN:ABCB1-variant-count CUI
KFGENEBIN (Entity type)
Gene has variants
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)

1-(1-Biphenyl-4-yl-2-phenyl-methyl)-1H-imidazole::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole (bifonazole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole( Bifanozole)::1-(Biphenyl-4-yl-phenyl-methyl)-1H-imidazole(Bifonazole)::1-(biphenyl-4-yl-phenyl-methyl)-1H-imidazole::BIFONAZOLE::CHEMBL277535::US9144538, Bifonazole::cid_2378
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)
-0.004072682

Endothelial cell of venule
Anatomy (Entity type)
Has marker gene in heart
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ABCB1
Gene (Entity type)
-0.0033512197

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

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