rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MICAL2 Gene (Entity type)	-0.003570531
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BAALC Gene (Entity type)	-0.0035492892
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.0062416308
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	KIF14 Gene (Entity type)	0.0035124905
2-[(diphenylmethyl)sulfinyl]acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	0.4126498401165008
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TOP2A Gene (Entity type)	0.0031362223
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	IGFBP5 Gene (Entity type)	0.0034869662
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CDC20 Gene (Entity type)	0.00607998
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SNAP25 Gene (Entity type)	-0.00426922
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	SKIC2 Gene (Entity type)	0.0031465285

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MICAL2
Gene (Entity type)
-0.003570531

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
BAALC
Gene (Entity type)
-0.0035492892

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.0062416308

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
KIF14
Gene (Entity type)
0.0035124905

2-[(diphenylmethyl)sulfinyl]acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
0.4126498401165008

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TOP2A
Gene (Entity type)
0.0031362223

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
IGFBP5
Gene (Entity type)
0.0034869662

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CDC20
Gene (Entity type)
0.00607998

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SNAP25
Gene (Entity type)
-0.00426922

rac-6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
SKIC2
Gene (Entity type)
0.0031465285

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