Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

MMP1 (Gene)

Ensembl Gene ID: ENSG00000196611

Entrez Gene ID: 4312

Description: matrix metallopeptidase 1

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MMP1's neighborhood in the knowledge graph.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MMP1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MMP1.

GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MMP1.

Gene Sets (3434)

LINCS L1000 Chem Pert Consensus Sigs (916)

A gene set library provided by LINCS

GlyGen

GlyGen Glycosylated Proteins 2022 (29)

A gene set library provided by GlyGen

LINCS L1000 CRISPR KO Consensus Sigs (1233)

A gene set library provided by LINCS

rummageo gene perturbations (131)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Aging Signatures 2021 (26)

A gene set library provided by GTEx

LINCS L1000 Consensus Median Signatures (854)

A gene set library provided by LINCS

rummageo chemical perturbations (237)

A gene set library provided by LINCS

Genotype Tissue Expression

GTEx Tissues V8 2023 (1)

A gene set library provided by GTEx

Illuminating the Druggable Genome

IDG Drug Targets 2022 (7)

A gene set library provided by IDG

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-pyridine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.0036163272
	SID11111453 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.005836661
	Trichloromethiazide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.0047621774
	paracetamol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.004058199
	eperezolid Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.0037172937
	6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.012240941
	Pentobarbital Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.00549196
	3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	-0.0034016513
	5-[2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]anilino]pyridine-3-carboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.0057521686
	Nizofenone Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.0034875043

4-[5-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-pyridine
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.0036163272

SID11111453
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.005836661

Trichloromethiazide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.0047621774

paracetamol
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.004058199

eperezolid
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.0037172937

6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.012240941

Pentobarbital
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.00549196

3-(1-{3-[5-(1-methyl-piperidin-4-ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
-0.0034016513

5-[2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]anilino]pyridine-3-carboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.0057521686

Nizofenone
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.0034875043

DISPLAY PER PAGE

Consortium

Community

Resources

@CFDE Workbench 2025

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2025

This repository is under review for potential modification in compliance with Administration directives.