CFDE Workbench
InfoDataCloudKnowledgetrainingcoordination
Search
Graph
Enrichment
Cross
Assistant
Data Matrix
Use Cases
Tools & Workflows
Submit
Documentation
CFDE Workbench

SKIC2 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:170A, DDX13, ENTREZ:6499, HGNC:10898, HLP, MIM:600478, NM_006929, NP_008860, SKI2, SKI2W, SKIV2, SKIV2L, SKIV2L1, Ski2 like RNA helicase, THES2, XM_011514815, XP_011513117, XR_001743586, XR_926301
Omim:OMIM:600478
Id:ENSG00000204351
Hgnc:HGNC:10898
Entrez:6499
Ensembl:ENSG00000204351
Description:SKI2 subunit of superkiller complex
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SKIC2's neighborhood in the knowledge graph.

Submit
Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SKIC2.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SKIC2.

Submit
Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SKIC2.

Submit
Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SKIC2.

Results found

Linked to

 

Label

Description

 

Gene Set

T60-Adrenal Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

T61-Colon Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

Gene Set

GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE193993 SSTR2 knockout 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE252944 AKT inhibition 7 v 14 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE235587 mitoxantrone KYSE-70 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE248770 STIM1 knockout Hep 3B2.1-7 Sorafenib 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE248770 sorafenib Hep 3B2.1-7 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE190178 MEK CDK8 inhibition 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE133749 BMPR2 overexpression endothelial cell 0 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    T60-Adrenal Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    T61-Colon Consensus

    Gene Set (Entity type)

    A Gene Set from MoTrPAC

  • Gene Set

    GSE254526 GSE254528 MI-1 Kasumi-1 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE193993 SSTR2 knockout 0 v 2 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 7 v 14 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE235587 mitoxantrone KYSE-70 2 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE248770 STIM1 knockout Hep 3B2.1-7 Sorafenib 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE248770 sorafenib Hep 3B2.1-7 0 v 1 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE190178 MEK CDK8 inhibition 1 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE133749 BMPR2 overexpression endothelial cell 0 v 4 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

    • DISPLAY PER PAGE
    CFDE Workbench
    Report a bug
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    @CFDE Workbench 2026
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.