NOP53 (Gene)

Description: NOP53 ribosome biogenesis factor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NOP53's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NOP53.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NOP53.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NOP53.

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Gene Sets (469)

LINCS L1000 Chem Pert Consensus Sigs (305)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (6)

A gene set library provided by IDG

LINCS L1000 CRISPR KO Consensus Sigs (157)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
Everolimus Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.0067441296
(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.013455408
SA-244587 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	-0.011096845
2-[[5-Chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]-amino]pyrimidin-4-yl]amino]-N-methylbenzamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.005050963
GSK-1059615 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.008427415
PF-04691502 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.0095458515
PI-103 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.006336698
taselisib Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.007578744
1-(4-{[4-(Dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.011042421
2-(1H-Indazol-4-yl)-6-(4-methanesul fonyl-piperazin-1-ylmethyl)-4-morph olin-4-yl-thieno[3,2-d]pyrimidine Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	NOP53 Gene (Entity type)	0.0043270546