PIEZO1 (Gene)

Description: piezo type mechanosensitive ion channel component 1 (Er blood group)

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PIEZO1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PIEZO1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PIEZO1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PIEZO1.

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Gene Sets (1268)

LINCS L1000 Chem Pert Consensus Sigs (668)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (11)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (11)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (576)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
KFGENEBIN:PIEZO1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)
hydrocortisone-acetate Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	0.01275579
2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid N-(tetrahydropyran-4-ylmethyl)amide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.00332031
(S)-4-(3-chloro-4-methoxybenzylamino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.0029320905
2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl]-phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol::2,6-di(tert-butyl)-4-{1-[3,5-di(tert-butyl)-4-hydroxyphenylsulfanyl]-1-methylethylsulfanyl}phenol(probucol)::2,6-di-tert-butyl-4-(2-(3,5-di-tert-butyl-4-hydroxyphenylthio)propan-2-ylthio)phenol::CHEMBL608::DH-581::Lorelco::PROBUCOL::US9182402, 14 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.0039372207
(2R,3S)-3-(isopropylamino)-1-(7-methyl-2,3-dihydro-1H-inden-4-yloxy)butan-2-ol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.010862903
Etiocholanolone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.017858965
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.0028744242
mifobate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.0038419792
CPI-1189 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	PIEZO1 Gene (Entity type)	-0.003407479