2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View 2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1H Gene (Entity type)	-0.0051162876
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PEG10 Gene (Entity type)	0.0027074749
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TCN1 Gene (Entity type)	0.0036673616
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1X Gene (Entity type)	-0.0048669633
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	GALNT6 Gene (Entity type)	0.0027914657
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	MT1HL1 Gene (Entity type)	-0.0042185117
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZNF395 Gene (Entity type)	0.0028221516
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	lacosamide Compound (Entity type)	0.3296786844730377
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	LGALS3 Gene (Entity type)	-0.0028598944
2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	SPARCL1 Gene (Entity type)	-0.0031845227

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1H
Gene (Entity type)
-0.0051162876

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PEG10
Gene (Entity type)
0.0027074749

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TCN1
Gene (Entity type)
0.0036673616

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1X
Gene (Entity type)
-0.0048669633

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
GALNT6
Gene (Entity type)
0.0027914657

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
MT1HL1
Gene (Entity type)
-0.0042185117

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZNF395
Gene (Entity type)
0.0028221516

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
lacosamide
Compound (Entity type)
0.3296786844730377

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
LGALS3
Gene (Entity type)
-0.0028598944

2-methoxy-N-(3-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)quinazolin-6-yl)allyl)acetamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
SPARCL1
Gene (Entity type)
-0.0031845227

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Knowledge Graph Assertions

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