EPS8 (Gene)

Description: EGFR pathway substrate 8, signaling adaptor

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View EPS8's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with EPS8.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using EPS8.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for EPS8.

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Gene Sets (1438)

LINCS L1000 Chem Pert Consensus Sigs (880)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (1)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (553)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (2)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
[3-(4-Bromo-2-fluoro-benzyl)-4-oxo-3,4-dihydro-phthalazin-1-yl]-acetic acid (ponalrestat) Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.010214901
Antazoline Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.022183852
strychnine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.009945466
docebenone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.03440379
Olmesartan Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.013934949
fenoprofen Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	-0.014884862
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	0.0054630707
(R)-5-((2-(3-aminopiperidin-1-yl)biphenyl-3-yl)methylene)thiazolidine-2,4-dione Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	0.004195729
SA-1922975 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	0.013460934
2-(4-tert-Butyl-2,6-dimethyl-benzyl)-4,5-dihydro-1H-imidazole Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	0.018329026