(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View (S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	LY6E Gene (Entity type)	0.0044815904
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NDRG1 Gene (Entity type)	-0.003819599
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BEX1 Gene (Entity type)	0.005300521
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TSPYL5 Gene (Entity type)	0.005197027
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	EPS8 Gene (Entity type)	0.0054630707
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	S100A7 Gene (Entity type)	-0.0050070407
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ASNS Gene (Entity type)	-0.004418559
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CKB Gene (Entity type)	-0.004179121
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TFPI Gene (Entity type)	0.0050044837
(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	AZD6482 Compound (Entity type)	0.3817191421985626

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
LY6E
Gene (Entity type)
0.0044815904

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NDRG1
Gene (Entity type)
-0.003819599

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BEX1
Gene (Entity type)
0.005300521

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TSPYL5
Gene (Entity type)
0.005197027

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
EPS8
Gene (Entity type)
0.0054630707

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
S100A7
Gene (Entity type)
-0.0050070407

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ASNS
Gene (Entity type)
-0.004418559

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CKB
Gene (Entity type)
-0.004179121

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TFPI
Gene (Entity type)
0.0050044837

(S)-N1-(2-tert-butyl-4'-methyl-4,5'-bithiazol-2'-yl)pyrrolidine-1,2-dicarboxamide
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
AZD6482
Compound (Entity type)
0.3817191421985626

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Knowledge Graph Assertions

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