BUB1 (Gene)

Description: BUB1 mitotic checkpoint serine/threonine kinase

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View BUB1's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with BUB1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using BUB1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for BUB1.

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Gene Sets (579)

LINCS L1000 Chem Pert Consensus Sigs (388)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (2)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (2)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (179)

A gene set library provided by LINCS

GTEx Aging Signatures 2021 (8)

A gene set library provided by GTEx

Knowledge Graph Assertions

Source	Relation	Target	Evidence
methotrexate Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	-0.008435287
Fumonisin-b1 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	0.0053618406
MK-5108 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	0.005583499
(S)-4,11-Diethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	-0.013344068
VX-680/MK-0457 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	0.004657801
YK-4279 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	0.009198843
Teniposide Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	-0.016886268
amsacrine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	-0.008734057
KFGENEBIN:BUB1-variant-count CUI KFGENEBIN (Entity type)	Gene has variants Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)
Nutlin-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	BUB1 Gene (Entity type)	-0.0035088519