Nutlin-2 (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Nutlin-2's neighborhood in the knowledge graph.

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Knowledge Graph Assertions

Source	Relation	Target	Evidence
Nutlin-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	-0.0031897954
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZMAT3 Gene (Entity type)	0.0057042204
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53I3 Gene (Entity type)	0.0026422585
4-{[(2R,3S,4R,5S)-3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Nutlin-2 Compound (Entity type)	0.5140794515609741
Nutlin-2 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Compound (Entity type)	0.661383330821991
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIGAR Gene (Entity type)	0.0038098895
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HOXB2 Gene (Entity type)	0.0032952924
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BTG2 Gene (Entity type)	0.0028363944
Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	0.003184346
CX-5461 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Nutlin-2 Compound (Entity type)	0.4750047922134399

Nutlin-2
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
-0.0031897954

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZMAT3
Gene (Entity type)
0.0057042204

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP53I3
Gene (Entity type)
0.0026422585

4-{[(2R,3S,4R,5S)-3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Nutlin-2
Compound (Entity type)
0.5140794515609741

Nutlin-2
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Compound (Entity type)
0.661383330821991

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIGAR
Gene (Entity type)
0.0038098895

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HOXB2
Gene (Entity type)
0.0032952924

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BTG2
Gene (Entity type)
0.0028363944

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A3
Gene (Entity type)
0.003184346

CX-5461
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Nutlin-2
Compound (Entity type)
0.4750047922134399

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