Information PortalData Portal

Data Matrix

Tools & Workflows

Documentation

Nutlin-2 (Compound)

Description: A compound in the knowledge graph

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View Nutlin-2's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
Loading results...

DISPLAY PER PAGE

Report a bug

Data & Metadata

Tools & Use Cases

@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Data & Metadata

Tools & Use Cases

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	Nutlin-2 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CHAC1 Gene (Entity type)	-0.0031897954
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ZMAT3 Gene (Entity type)	0.0057042204
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TP53I3 Gene (Entity type)	0.0026422585
	4-{[(2R,3S,4R,5S)-3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Nutlin-2 Compound (Entity type)	0.5140794515609741
	Nutlin-2 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid Compound (Entity type)	0.661383330821991
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	TIGAR Gene (Entity type)	0.0038098895
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	HOXB2 Gene (Entity type)	0.0032952924
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	BTG2 Gene (Entity type)	0.0028363944
	Nutlin-2 Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ALDH1A3 Gene (Entity type)	0.003184346
	CX-5461 Compound (Entity type)	In similarity relationship with Knowledge Graph Relation (Entity type)	Nutlin-2 Compound (Entity type)	0.4750047922134399

Nutlin-2
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CHAC1
Gene (Entity type)
-0.0031897954

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ZMAT3
Gene (Entity type)
0.0057042204

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TP53I3
Gene (Entity type)
0.0026422585

4-{[(2R,3S,4R,5S)-3-(3-Chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Nutlin-2
Compound (Entity type)
0.5140794515609741

Nutlin-2
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid
Compound (Entity type)
0.661383330821991

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
TIGAR
Gene (Entity type)
0.0038098895

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
HOXB2
Gene (Entity type)
0.0032952924

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
BTG2
Gene (Entity type)
0.0028363944

Nutlin-2
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ALDH1A3
Gene (Entity type)
0.003184346

CX-5461
Compound (Entity type)
In similarity relationship with
Knowledge Graph Relation (Entity type)
Nutlin-2
Compound (Entity type)
0.4750047922134399

DISPLAY PER PAGE