APBB2 (Gene)

Description: amyloid beta precursor protein binding family B member 2

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View APBB2's neighborhood in the knowledge graph.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with APBB2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using APBB2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for APBB2.

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Gene Sets (799)

LINCS L1000 Chem Pert Consensus Sigs (697)

A gene set library provided by LINCS

ARCHS4 IDG Coexp (5)

A gene set library provided by IDG

KOMP2 Mouse Phenotypes 2022 (5)

A gene set library provided by KOMP2

LINCS L1000 CRISPR KO Consensus Sigs (91)

A gene set library provided by LINCS

Molecular Transducers of Physical Activity Consortium

MoTrPAC Endurance Trained Rats 2023 (1)

A gene set library provided by MoTrPAC

Knowledge Graph Assertions

Source	Relation	Target	Evidence
SD-6-035-B3 Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.007120844
2-methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2,4-dihydro-1H-[1,3]oxazino[5,4-c]quinolin-1-yl)phenyl)propanenitrile Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.022886304
Trimebutine Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.0050438666
4-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	0.0071113072
febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.0030032531
Entacapone Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.009186991
pranlukast Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.0035498377
bis-tyrphostin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	0.008878858
Mianserin Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	0.005232321
levosalbutamol Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.0060032043