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febuxostat (Compound)

Description: A compound in the knowledge graph

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View febuxostat's neighborhood in the knowledge graph.

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
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@CFDE Workbench 2024

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2024

Knowledge Graph Assertions

	Source	Relation	Target	Evidence
	febuxostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	PLAC8 Gene (Entity type)	0.0028310646
	febuxostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	ADD3 Gene (Entity type)	0.0030352916
	febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	ARNT2 Gene (Entity type)	-0.0034769552
	febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	COL4A5 Gene (Entity type)	-0.0029851012
	febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	APBB2 Gene (Entity type)	-0.0030032531
	febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	NFATC3 Gene (Entity type)	-0.002522246
	febuxostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	CEACAM6 Gene (Entity type)	0.0030915604
	febuxostat Compound (Entity type)	Positively regulates Knowledge Graph Relation (Entity type)	MMP1 Gene (Entity type)	0.0032035136
	febuxostat Compound (Entity type)	Negatively regulates Knowledge Graph Relation (Entity type)	CXCL14 Gene (Entity type)	-0.0026546547
	febuxostat Compound (Entity type)	Bioactivity Knowledge Graph Relation (Entity type)	Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Protein (Entity type)	IC50

febuxostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
PLAC8
Gene (Entity type)
0.0028310646

febuxostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
ADD3
Gene (Entity type)
0.0030352916

febuxostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
ARNT2
Gene (Entity type)
-0.0034769552

febuxostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
COL4A5
Gene (Entity type)
-0.0029851012

febuxostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
APBB2
Gene (Entity type)
-0.0030032531

febuxostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
NFATC3
Gene (Entity type)
-0.002522246

febuxostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
CEACAM6
Gene (Entity type)
0.0030915604

febuxostat
Compound (Entity type)
Positively regulates
Knowledge Graph Relation (Entity type)
MMP1
Gene (Entity type)
0.0032035136

febuxostat
Compound (Entity type)
Negatively regulates
Knowledge Graph Relation (Entity type)
CXCL14
Gene (Entity type)
-0.0026546547

febuxostat
Compound (Entity type)
Bioactivity
Knowledge Graph Relation (Entity type)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase
Protein (Entity type)
IC50

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